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Nasal spray flu vaccine 'ineffective and should not be used,' say AAP

The nasal spray flu vaccine is ineffective, and youngsters aged 6 months and older should obtain the flu shot in the course of the 2016-2017 season for the absolute best safety towards influenza. This is the advice from the American Academy of Pediatrics, forming a part of a brand new coverage assertion.
[A child being given a nasal spray vaccine]
Research revealed that the nasal spray flu vaccine provided solely three % safety in the course of the 2015-2016 flu season.


The assertion – lately revealed within the journal Pediatrics – helps earlier suggestions from the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC), which voted that the nasal spray flu vaccine should not be used this flu season.


The suggestions from each the American Academy of Pediatrics (AAP) and ACIP stem from analysis revealed in May, offering preliminary proof that the nasal spray flu vaccine – or the reside attenuated influenza vaccine (LAIV) – provided low safety towards sure influenza strains between 2013-2016.


Those knowledge – gathered from the United States Influenza Vaccine Effectiveness Network – revealed that amongst youngsters aged 2-17 years, LAIV provided solely three % safety towards any flu virus through the 2015-2016 flu season.


In comparability, the inactivated influenza vaccine (IIV) – the injected flu vaccine – provided 63 % safety towards any flu virus.


LAIV – marketed as FluMist and produced by MedImmune, a subsidiary of AstraZeneca – was additionally discovered to supply poor or lower-than-expected safety towards influenza in the course of the 2013-2014 and 2014-2015 flu seasons, the analysis revealed.

Flu shot doubtless to offer greater degree of safety for youngsters


Previous analysis had recommended that LAIV was simply as – if not extra – efficient than the flu shot; LAIV accommodates stay flu viruses, which should set off a stronger immune response than vaccines with inactivated flu viruses, reminiscent of IIV.


According to the CDC, the rationale for the poor effectiveness of the LAIV vaccine is unknown.


Based on the current proof demonstrating the low safety LAIV presents towards influenza, the AAP recommend that each one youngsters aged 6 months and older be vaccinated with IIV through the 2016-2017 flu season – not the flu nasal spray.

“New analysis exhibits that the flu shot offered considerably higher safety in current flu seasons in contrast with the nasal spray vaccine.


We need to present youngsters with the most effective safety potential towards flu, and these current research present the flu shot is probably going to offer a better degree of safety.”

Statement co-author Dr. Henry H. Bernstein, AAP member


Children aged 6 months to 9 years require one dose of IIV if they’ve beforehand acquired two or extra doses of IIV or LAIV earlier than July 1, 2016, the AAP word, or two doses if they’ve acquired fewer than two doses of IIV or LAIV earlier than July 1, 2016. Children aged 9 years and older solely require one dose.

Further AAP flu vaccine suggestions


As a part of the brand new coverage assertion, the AAP advocate flu vaccination for all youngsters and adolescents with medical circumstances that would improve their danger of flu problems, akin to asthma and sickle cell anemia.


Caregivers and family contacts of those youngsters should additionally be vaccinated.


The AAP additionally encourage pregnant ladies to obtain the flu shot, because of the excessive danger of flu problems for each mom and baby. They word that a mom’s flu vaccination can shield her baby within the first 6 months of life.


“Pregnant women can help protect themselves and their unborn children by getting the vaccine,” says Dr. Wendy Sue Swanson, member of the AAP. “Breast-feeding also offers newborns added protection against the flu. Because the flu virus is common and unpredictable, it can cause serious complications even in healthy children.”


The coverage assertion additionally hails obligatory seasonal flu vaccinations for health care professionals (HCPs) as an “ethical, just, and necessary” means to enhance affected person security.


“HCPs should act as role models for both their patients and colleagues by receiving influenza vaccination annually and by letting others know that they have received vaccine, highlighting the safety and effectiveness of annual influenza vaccination,” say the AAP.


HCPs should begin providing the flu vaccine to adults and youngsters from October this yr, the AAP advocate, noting that immunizing as early as attainable should supply safety for the complete 2016-2017 season.


Flu vaccination should proceed to be provided till June 30, 2017, nevertheless, as a result of outbreaks can happen late within the season.

“The influenza vaccine is an essential, every-year vaccine for infants beginning at 6 months, children and teens. Protecting children from influenza with the vaccine, early in the respiratory season, is the best protection pediatricians and parents can provide.”

Dr. Wendy Sue Swanson


Learn how flu vaccination in pregnancy may protect infants in early life.


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